Yuefeng Wang, MD, PhD

Roles
Radiation Oncology
Specialty
Lung Cancer   |   Head and Neck Cancer   |   Genitourinary Cancers   |   Gynecologic Cancer   |   Prostate Cancer

About Me

Education

  • MD, University of Tennessee Health Science Center
  • PhD, Chinese Academy of Sciences

Residency

  • Radiation Oncology – University of Mississippi Medical Center
  • Radiation Oncology – West Cancer Center, University of Tennessee Health Science Center

Fellowship

  • Preliminary Medicine – University of Tennessee Health Science Center

Board Certification

  • Radiation Oncology

Awards and Honors

  • ASCO Merit Award (2019)
  • Young Investigator Award (2018)
  • Emory Medical Scholar Award (2011)
  • AACR-Eli-Lilly Scholar-in-Training Award (2006)
  • NIH Scholarship (2004)

Research and Publications

Publication List

  1. Yuefeng Wang, Todd Tillmanns, Noam VanderWalde, Bradley Somer, Ari VanderWalde, Lee Schwartzberg, Matthew T. Ballo. Comparison of Chemotherapy vs Chemotherapy Plus Total Hysterectomy for Women With Uterine Cancer With Distant Organ Metastasis. Accepted by JAMA Network Open, In Press.
  2. Yuefeng Wang, Gieschen H, Greenberger M, Yu X, Tian G, VanderWalde N, Stockstill T, Izaguirre E, Farmer M, Rinker L, Somer B, Ballo MT. Survival after Robotic Assisted Prostatectomy for Localized Prostate Cancer: an Epidemiologic Study. Annals of Surgery, 2019 Oct 28. doi: 10.1097/SLA.0000000000003637.
  3. Yuefeng Wang, Manjari Pandey, & Matthew T. Ballo. Integration of Tumor Treating Fields into the Multidisciplinary Management of Patients with Solid Malignancies. The Oncologist, 2019 Aug 23. pii: theoncologist.2017-0603. doi: 10.1634/theoncologist.2017-0603. [Epub ahead of print]
  4. Yuefeng Wang, VanderWalde N, Ballo MT. Loco-regional treatments in metastatic cervical cancer patients: from level of evidence to ethical considerations – In Reply. JAMA Oncology,2019 Mar 7. doi: 10.1001/jamaoncol.2019.0028. [Epub ahead of print]
  5. Maksym Tsytlonok*, Hugo Sanabria*, Yuefeng Wang*(co-first author), Suren Felekyan, Katherina Hemmen, Mi-Kyung Yun, Brett Waddell, Cheon-Gil Park, Sivaraja Vaithiyalingam, Luigi Iconaru, Stephen W. White, Peter Tompa, Claus A. M. Seidel, Richard Kriwacki. Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation. (Nature Communications, 2019 Apr 11;10(1):1676. doi: 10.1038/s41467-019-09446-w)
  6. Yuefeng Wang, Yu X, Zhao N, Wang, J, Lin C, Izaguirre E, Famer M, Tian G, Somer B, Dubal N, Schwartz D, Ballo MT, Vanderwalde N. Definitive Pelvic Radiotherapy and Survival of Patients with Newly Diagnosed Metastatic Anal Cancer. J Natl Compr Canc Netw., 2019 Jan;17(1):29-37.
  7. Yuefeng Wang, Farmer M, Izaguirre E, Schwartz D, Somer B, Tillmanns T, Ballo MT. Association of Definitive Pelvic Radiotherapy with Survival Among Patients with Newly Diagnosed Metastatic Cervical Cancer. (2018) JAMA Oncology, 2018 Sep 1;4(9):1288-1291.
  8. Yuefeng Wang, Tian Liu, Peter J. Rossi, Deborah Watkins-Bruner, Wayland Hsiao, Sherrie Cooper, Xiaofeng Yang, and Ashesh B. Jani. Influence of Vascular Comorbidities and Race on Erectile Dysfunction after Prostate Cancer Radiotherapy. (2013) Journal of Sexual Medicine, 10(8):2108-14. [Reported as Breaking News by the Renal and Urology News on 09/29/2013]
  9. Yuefeng Wang, Marie Assem, Rose Matthew, Jack Sublet, Limin Xiao, Martine F. Roussel, Richard W. Kriwacki. Intrinsic Disorder Mediates the Diverse Cell Cycle Regulatory Functions of the Cyclin dependent kinase Inhibitor, p21Cip1. (2011) Nature Chemical Biology, 7(4), 214-21. [Highlighted as News and Views by Nature Chemical Biology on 2011]
  10. Matthias Grimmle*, Yuefeng Wang*(co-first author), Thomas Mund, Zoran Cilenšek, Eva-Maria Keidel, M. Brett Waddell, Heidelinde Jäkel, Michael Kullmann, Richard W. Kriwacki, and Ludger Hengst. Cdk-Inhibitory Activity and Stability of p27Kip1 Are Directly Regulated by Oncogenic Tyrosine Kinases. (2007) Cell, 128(2), 269-280. [Highlighted as News and Views by Cell, Nature Review Cancer, and Chemical & Engineering News on 2007]
  11. Yuefeng Wang, Igor Filippov, Christain Richter, and Richard W. Kriwacki. Solution NMR Studies of an Intrinsically Unstructured Protein within a Dilute, 75 kDa Eukaryotic Protein Assembly; Probing the Practical Limits for Efficiently Assigning Polypeptide Backbone Resonances. (2005) ChemBioChem, 6(12), 2242-6.
  12. Eilyn R. Lacy*, Yuefeng Wang*(co-first author), Jeremy Post, Amanda Nourse, William Webb, Marina Mapelli, Andrea Musacchio, Gary Siuzdak and Richard W. Kriwacki. Molecular basis for the specificity of p27 toward cyclin-dependent kinases that regulate cell division. (2005) Journal of Molecular Biology 349(4), 764-73.
  13. Yuefeng Wang, Xiang Chen, Naixia Zhang, Gong Wu, Houming Wu. The solution structure of BmTx3B, a member of the scorpion toxin subfamily alpha-KTx 16. (2005) Proteins: Structure, Function and Bioinformatics, 58(2), 489-97.
  14. Yuefeng Wang, Hong Dou, Chunyang Cao, Naixia Zhang, Jingbiao Ma, Jifang Mao, and Houming Wu. Solution structure and biological activity of recombinant salmon calcitonin S-sulfonated analog. (2003) Biochemical and Biophysical Research Communications, 306, 582–589.
  15. Xiaofeng Yang, Srini Tridandapani, Jonathan J. Beitler, David S. Yu, Ning Wu, Yuefeng Wang, Deborah W. Bruner, Walter J. Curranand Tian Liu. Ultrasonic Nakagami-parameter characterization of parotid-gland injury following head-and-neck radiotherapy: A feasibility study of late toxicity. (2014) Medical Physics, 2014 Feb;41(2):022903.
  16. Yi Gao, Allen Tannenbaum, Hao Chen, Mylin Torres, Emi Yoshida, Xiaofeng Yang, Yuefeng Wang, Walter Curran, Tian Liu. Automated Skin Segmentation in Ultrasonic Evaluation of Skin Toxicity in Breast Cancer Radiotherapy. (2013) Ultrasound in Med & Biol., 39(11), 2166-75.
  17. Charles A. Galea, Yuefeng Wang, Sivashankar G. Sivakolundu and Richard W. Kriwacki. Regulation of Cell Division by Intrinsically Unstructured Proteins; Intrinsic Flexibility, Modularity and Signaling Conduits. (2008) Biochemistry, 47(29):7598-609.
  18. Charles A. Galea, Amanda Nourse, Yuefeng Wang, Sivashankar G. Sivakolundu, William T. Heller and Richard W Kriwacki. The Role of Intrinsic Flexibility in Signal Transduction Mediated by the Cell Cycle Regulator, p27Kip1. (2008) Journal of Molecular Biology, 376 (3):827-38.
  19. John B. Jordan, Helena Kovacs, Yuefeng Wang, Mehdi Mobli, Rensheng Luo, Clemens Anklin, Jeffrey C. Hoch, and Richard W. Kriwacki. 3D 13C-detected CH3-TOCSY and selective protonation: A novel route to resonance assignment and global fold determination. (2006) Journal of American Chemical Society, 128(28), 9119 – 9128.
  20. Naixia Zhang,Minghua Li,Xiang Chen, Chunyang Cao,Yuefeng Wang, Gong Wu, Guoyuan Hu, Houming Wu. Solution structure of BmKK4, the first member of subfamily alpha-KTx 17 of scorpion toxins. (2004) Biochemistry, 43(39), 12469-76.
  21. Naixia Zhang,Minghua Li,Xiang Chen,Yuefeng Wang, Gong Wu, Guoyuan Hu, Houming Wu. Solution structure of BmKK2, a new potassium channel blocker from the venom of chinese scorpion Buthus martensi Karsch. (2004) Proteins: Structure, Function and Bioinformatics, 55(4), 835-45.
  22. Chunyang Cao, Qi Zhang, Zhiqian Wang, Yuefeng Wang, Houming Wu, Yunhua Wang. 1H NMR studies of the effect of mutation at Valine45 on heme microenvironment of cytochrome b5. (2003) Biochimie, 85(10), 1007-16.
  23. Nai-Xia Zhang, Gong Wu, Yuefeng Wang, Zhong-Hua Wang, Chuan-Li Feng, Hou-Ming Wu. Purification and Primary Structure of a Toxin-like Peptide BmK622 from the Venom of Chinese Scorpion Buthus martensii Karsch. (2003) Acta Chim. Sinica, 61(4), 630-634.
  24. Ming-Hua Li, Yuefeng Wang, Xue-Qin Chen, Nai-Xia Zhang, Hou-Ming Wu, Guo-Yuan Hu. BmTx3B, a novel scorpion toxin from Buthus martensi Karsch, inhibits the delayed rectifier potassium current in rat hippocampal neurons. (2003) Acta Pharmacologica Sinica, 24(10):1016-20.
  25. Feng Gao, Yuefeng Wang, Yinlin Sha, Yinling Li, Luhua Lai and Houming Wu. b-turn formation by a six-residue linear peptide in solution; (2002) Journal of Peptide Research, 60(2), 75-80.
  26. Chunyang Cao, Yuefeng Wang, Houming Wu, Zhiqiang Wang, Yunhua Wang. NMR Preliminary study on cytochrome b5 mutant V45H; (2001) Acta Chim. Sinica, 59(4), 578-586.
  27. Feng Gao, Yinlin Sha, Yang Qiu, Yuefeng Wang, Yinling Li, Luhua Lai and Houming Wu. Solution conformation study on a b-turn forming peptide; (2001) Acta Physico-chimica Sinica, 17(7), 619-621.

Selected Meeting Abstracts/Presentations

  1. Yuefeng Wang, Todd Tillmanns, Noam VanderWalde, Bradley Somer, Ari VanderWalde, Lee Schwartzberg, Matthew T. Ballo. Association of Total Hysterectomy with Survival among Newly Diagnosed Uterine Cancer Patients with Distant Organ Metastasis. ASCO annual meeting, Chicago, May 2019.
  2. Yuefeng Wang, Farmer M, Izaguirre E, Schwartz D, Somer B, Tillmanns T, Ballo MT. Association of Definitive Pelvic Radiotherapy with Survival Among Patients with Newly Diagnosed Metastatic Cervical Cancer. CSTRO/SANTRO, Taizhou, Zhejiang, China, 2018.
  3. Yuefeng Wang, Gieschen H, Greenberger M, VanderWalde N, Yu X, Stockstill T, Izaguirre E, Farmer M, Rinker L, Somer B, Ballo MT. Survival after Robotic Prostatectomy for Localized Prostate Cancer: an Epidemiologic Study. Annual West Oncology Conference, Memphis, TN, November 2018.
  4. Yuefeng Wang, Yu X, Zhao N, Wang, J, Lin C, Enrique I, Famer M, Tian G, Somer B, Dubal N, Schwartz D, Ballo MT, Vanderwalde N. Definitive Pelvic Radiotherapy and Survival of Patients with Newly Diagnosed Metastatic Anal Cancer. Annual West Oncology Conference, Memphis, TN, November 2018.
  5.   Yuefeng Wang, Farmer M, Izaguirre E, Yu X, Vanderwalde N, Schwartz D, Rinker L, Somer B, Tillmanns T, Ballo MT. Impacts of Definitive Pelvic Radiotherapy on the Survival of Patients with Newly Diagnosed Metastatic Cervical Cancer. Annual West Oncology Conference, Memphis, TN, November 2018.
  6. Yuefeng Wang, Yu X, Zhao N, Wang, J, Lin C, Enrique I, Famer M, Tian G, Somer B, Dubal N, Schwartz D, Ballo MT, Vanderwalde N. Definitive Pelvic Radiotherapy and Survival of Patients with Newly Diagnosed Metastatic Anal Cancer. ASTRO 60th Annual Meeting, San Antonia, TX, October 2018.
  7. Yuefeng Wang, Farmer M, Izaguirre E, Yu X, Vanderwalde N, Schwartz D, Rinker L, Somer B, Tillmanns T, Ballo MT. Impacts of Definitive Pelvic Radiotherapy on the Survival of Patients with Newly Diagnosed Metastatic Cervical Cancer. ASTRO 60th Annual Meeting, San Antonia, TX, October 2018.
  8. Yuefeng Wang, Pradeep Patra, Matthew Wilson, Noam VanderWalde and Matthew Ballo. Dosimetry Evaluation of Custom-made Eye Plaque for Brachytherapy of Ocular Melanoma. ASTRO 57th Annual Meeting, San Antonia, TX, October 2015.
  9. Yuefeng Wang, Tian Liu, Peter J. Rossi, Deborah Watkins-Bruner, Wayland Hsiao, Sherrie Cooper, Xiaofeng Yang, and Ashesh B. Jani. Influence of Vascular Comorbidities and Race on Erectile Dysfunction after Prostate Cancer Radiotherapy. ASTRO 55th Annual Meeting, Atlanta, GA, September 2013.
  10. Yuefeng Wang, Tian Liu, Peter J. Rossi, Deborah Watkins-Bruner, Wayland Hsiao, Sherrie Cooper, Xiaofeng Yang, and Ashesh B. Influence of Vascular Comorbidities and Race on Erectile Dysfunction after Prostate Cancer Radiotherapy. ASCO Genitourinary Cancers Symposium, San Francisco, CA, February 2012.
  11. Yuefeng Wang, Tian Liu, Peter J. Rossi, Deborah Watkins-Bruner, Wayland Hsiao, Sherrie Cooper, Xiaofeng Yang, and Ashesh B. Jani. Influence of Vascular Comorbidities and Race on Erectile Dysfunction after Prostate Cancer Radiotherapy. UTHSC College of Medicine 2012 AOA Medical Student Research Poster Session.
  12. Yuefeng Wang, Marie Assem, Rose Matthew, Jack Sublet, Limin Xiao, Martine F. Roussel, Richard W. Kriwacki. Intrinsic Disorder Mediates the Diverse Cell Cycle Regulatory Functions of the Cyclin dependent kinase Inhibitor, p21Cip1. The 14th International p53 Workshop, Shanghai, China, October 2008.
  13. Yuefeng Wang, Ludger Hengst, Brett Waddell, and Richard Kriwacki. Modulating p27 function through phosphorylation: A two-step mechanism leading to destruction. (2006) Proceedings of American Association for Cancer Research, 47: 1322.14.    Yuefeng Wang, Ludger Hengst and Richard W. Kriwacki. (2006) Modulating p27 Function Through Phosphorylation; A Two-step Mechanism Leading to Destruction. Keystone Symposia: Frontiers in Structural Biology, Keystone, Colorado, USA. Jan 29-Feb 3. 15.    Yuefeng Wang, Ludger Hengst and Richard W. Kriwacki. (2005) Modulating p27 Function Through Phosphorylation; A Two-step Mechanism Leading to Destruction. 57th Southeast / 61st Southwest Joint Regional Meeting of the American Chemical Society, November 1-4.
  14. 16.    Yuefeng Wang, Igor Filippov, Limin Xiao, Christain Richter, and Richard W. Kriwacki. (2004) Solution NMR study of p21 bound to Cdk2 (Cyclin Dependent Kinase 2) and Cyclin A, a 75 kDa ternary complex. Keystone symposia: Frontiers in Structural Biology, Snowbird, Utah, April 13-19.