Posts By: Jamie Crosno

West Cancer Center has modeled research driven, patient centered oncology care for over 40 years with a reputation for educating and advancing cancer treatments in the Midsouth, Nationally and Internationally. Their 6th Annual West Oncology Conference, usually held at the Guest house at Graceland, was held virtually on February 26 with a distinguished panel of… Read more »

Abstract The phosphatidylinositol-3-kinase (PI3K) pathway is frequently dysregulated in human breast cancer. Approximately 30%of all patients with breast cancer will carry mutations of the PIK3CA gene, which encodes the PI3K catalytic subunit isoform p110a. Mutations in PIK3CA have been associated with resistance to endocrine therapy, HER2-directed therapy, and cytotoxic therapy. Early trials of pan-PI3K inhibitors… Read more »