Stage 0

Abnormal cells are found in tissue lining the inside of the bladder. These abnormal cells may become cancer and spread into nearby normal tissue.

Stage I

Cancer has formed and spread to the layer of connective tissue next to the inner lining of the bladder.

Stage II

Cancer has spread to the layers of muscle tissue of the bladder.

Stage IIIA

  • Cancer has spread from the bladder to the layer of fat surrounding the bladder and may have spread to the reproductive organs (prostate, seminal vesicles, uterus, or vagina) and cancer has not spread to lymph nodes; or
  • Cancer has spread from the bladder to one lymph node in the pelvis that is not near the common iliac arteries (major arteries in the pelvis).

Stage IIIB

Cancer has spread from the bladder to more than one lymph node in the pelvis that is not near the common iliac arteries or to at least one lymph node that is near the common iliac arteries.

Stage IVA

  • Cancer has spread from the bladder to the wall of the abdomen or pelvis; or
  • Cancer has spread to lymph nodes that are above the common iliac arteries (major arteries in the pelvis)

Stage IVB

Cancer has spread to other parts of the body, such as the lung, bone, or liver

*Source: National Cancer Institute, October 19, 2018

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